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Analysis Of Radiation

576 words - 3 pages

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Radiation Oncology Therapy Comparison AlgorithmNameClassInstitutionDateAbstractPurpose/ObjectivesThe aim of the study was to compare and validate a new dosage calculation algorithm, Acruros XB (AXB). Validation will be used to determine the effectiveness of AXB for computing dosage for radiation therapy, which is used in Eclipse treatment plans (TPS). An evaluation will be made by comparing the doismetric AXB data with an anisotropic analytical algorithm called AAA, using RTOG 0813 factors. The RTOG 0813 factors are used because stereotactic body radiation therapy (SBRT) requires the use of dosage calculation algorithms that are capable of heterogeneity corrections for dosage computations. The study also was used to ...view middle of the document...

Treatment procedures were designed with AAA, which included correction for heterogeneity. AAA plans were re-calculated with AXB, which included correction for heterogeneity. The re-calculation ensured beam parameters were identical and contained an equal amount of monitor units. Comparisons between AXB and AAA plans included the following parameters for RTOG 0813: prescription isodose volume ratio with PTV (R100%), prescription isodose volume at 50% ratio with PTV (R50%), prescription dosage percentage of max dosage of 2 cm from the PTV in whichever direction (D2cm), and ipsilateral lung percentage for receiving dosage equal to or greater than 20 Gy (V20).ResultsResults from the phantom study revealed that the data obtained for AXB had measurements that were in better agreement with a range difference of -1.7% to 2.8%. The results for AAA demonstrated a greater disagreement from measurements with range differences of 4.1% to 12.5% at field dimensions of 5x5 cm2 and 1.4% to 6.8% at field dimensions of 10x10 cm2. Results for RTOG SBRT (lung trial) demonstrated that AXB measurements were lower for R100%, R50%, and D2cm at percentages of 4.9%, 1.15%, and 1.6%, correspondingly. However, the measurements were higher for V20 (ipsilateral lung) by a percentage of 1.09% compared to AAA plans.ConclusionsThe comparison between AAA and AXB revealed that AXB had more actuate measurements for dosage predictions in a material equivalent to water that is expanded further than low density mediums. The results for doismetric measurements in the study demonstrated that both AAA and AXB are capable of satisfying the dosimeter standards set by RTOG 0813. AXB calculations generated were significantly lower for R100%, R50%, and D2cm, but greater for V20 compared to calculations from AAA.

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