Phenylketonuria's Culprit: Amino Acids - Biochemistry - Research Paper Draft

602 words - 3 pages

Kelly 1
Sara Kelly
Dr. Holloway
GMS 6201: General Medical Biochemistry
June 17, 2018
The Culprit of Phenylketonuria: Amino Acids
Babies are indeed a bundle of joy. Unfortunately, they are susceptible to diseases and
disorders while in the womb and as soon as they are delivered. Statistics state that 1 in 10,000 -
15,000 newborns in the United States are diagnosed with Phenylketonuria (Mayo Clinic Staff),
which is better known as PKU. How the disorder is inherited, signs and symptoms, and life
expectancy are some of the topics that parent’s usually ask about. In the end, PKU is highly
treatable and the individual can expect to lead a normal life depending on their compliance with
treatment and their lifestyle; however, it can lead to death if it is not treated.
Phenylketonuria is inherited in an autosomal recessive pattern. Autosomal recessive
inheritance occurs when the individual has two copies of the altered gene. Each of the child’s
parent carries one copy of the altered gene, meaning that they are not affected by PKU nor do
they show symptoms of the disorder. A child that has the disorder, is missing a an enzyme by the
name of phenylalanine hydroxylase. This particular enzyme is necessary in catalyzing
phenylalanine in order to generate tyrosine. When the process is hindered, there is build up
phenylalanine which can cause damage to the child’s brain and significant intellectual
disabilities. The child may also have a low birth weight and and may grow at a slower rate than a
child in his/her’s age range (Lee).
Kelly 3
A PKU test is conducted within two days of the child’s birth. To ensure accurate results,
the test is completed after the child has ingested protein in their diet. It is likely that the child will
not receive sufficient proteins and nutrients on their restricted diet alo...

More like Phenylketonuria's Culprit: Amino Acids - Biochemistry - Research Paper Draft

Assignment 1 - HCC - Principals Of Biochemistry - Research Paper

1302 words - 6 pages ... environment would create high insulin conditions for cellular environments. Previous studies have shown that long-term administration of branched chain amino acids (BCAA) reduced the risk of HCC development in obese cirrhotic patients who were diagnosed with diabetes mellitus [Miuma 2012]. BCAA components are valine, leucine, and isoleucine. This study was designed to examine the effect of branched-chain amino acid (BCAA) on vascular endothelial ...

Biosynthesis Of Antibiotics Drug Daptomycin - Microbiology/postgraduate - Essay

1488 words - 6 pages ... Biosynthesis of peptide antibiotic Daptomycin Table of Contents Introduction ​3 Discussion ​3 Conclusion ​8 References ​9 Introduction Streptomyces roseosporus produces a peptide antibiotic that is cyclic in nature and made up of 13 amino acids. The antibiotic is known as Daptomycin and is effective against a wide variety of gram-positive bacteria. The antibiotic being highly effective in combating diseases caused by gram-positive organisms ...

Assignment On Phosphorylation In Yeast

2315 words - 10 pages ... given cell because there are many different kinds of proteins in any cell. It has been estimated that 1/10th to ½ of proteins are phosphorylated. Phosphorylation occurs mostly on multiple distinct sites on a given protein. Phosphorylation of any site on a given protein can change function of localization of that protein. Within a protein, phosphorylation can occur on several amino acids. Phosphorylation on serine is most common, followed ...

Evolution From A Molecular Perspective

3352 words - 14 pages ... molecule was built from exactly the same amino acid subunits connected in the same order along a chain, and had exactly the same weight. Most organisms have their own unique, individual chain of proteins to make up their hemoglobin, but all organisms share certain similarities, so striking that they are unable to be ignored. Let's take, for example, the first twenty-five amino acids in the alpha hemoglobin chains of 7 different animals: a human man ...

Paper On DNA

1661 words - 7 pages ... correct amino acids to the mRNA so they can be aligned in the right order by the ribosomes. (Heath,116) For protein synthesis to begin, the two parts of a ribosome must secure itself to a mRNA molecule.(Miller, 151)Methods and Materials:For the first part of the lab, colored paper clips were needed to construct two DNA strands. Each color paperclip represented one of the four nitrogenous bases. Black was used as adenine, white was thymine, blue ...

Pros And Cons Of Using Alternative Medicine For Mental Disorders - Psychopharmacology - Essay

1385 words - 6 pages ... alternative supplements would suggest replenishing the lacking nutrients to alleviate psychotic symptoms. St. John’s Wort, for example, contains amino acids that increase serotonin levels, ultimately reducing symptoms of depression (Solomon, & Adams, 2015). Therapists are not alone in their interests in CAM therapy. Patients are just as eager to subscribe to alternative treatments over conventional medication in regard to psychological issues. Some ...

What Enzymnes Are?

2561 words - 11 pages ... . aminotransferaseGlutamic acid + pyruvic acid→alpha-ketoglutaric acid + alanineThis is a reaction where the R group on the amino acid, glutamic acid, is exchanged with the R group on a keto acid, pyruvic acid. A new amino acid, alanine is formed along with a new keto acid, alpha-ketoglutaric acid. In this process non-essential amino acids could be made from the essential amino acids.Another group that enzymes categorizes into are the ...

My Name Is Is Free Deternameknwkn - Wohhhhh - Bam

576 words - 3 pages ... English 1012 Instructor: Cherry Lou Sy Research Paper Assignment Your research paper must be between 7-10 pages with standard MLA citation (20%) a research paper proposal, including list of possible sources; an annotated bibliography (10%) NO LATE PAPERS ACCEPTED Important Dates: Research Proposal Due: March 28 Research Essay Proposal Due with annotated bibliography: email    April 9 (for SEEK)– Rough Draft of Research Paper (bring 2 hardcopies ...

Food And Nutrition Test Outline - St Jean De Brebuff / Food And Nutrition - Research Paper

2533 words - 11 pages ... up of amino acids - the building blocks of proteins - Our bodies use 20 amino acids - 8 of these are ESSENTIAL because they cannot be made in the body - 12 of these are NOT ESSENTIAL because they are to be made in the body - Helps makes antibodies to fight diseases - Build body proteins - Provide essential amino acids not made in the body What types are there? 2 TYPES OF PROTEINS Complete Incomplete - Contains all 8 essential amino acids - Meat ...

Chemistry 1111. Lab Final Essay. Austin Community College

804 words - 4 pages Free ... binding to specific proteins(cell-surface receptors). Mark Bothwell’s research has found that the physiological functions of GF can be derived from their activity in tissue cultures which involve the regulation of cell proliferation and differentiation during embryonic development and wound healing. It has also found that the sequence of amino acids has been determined for many GF polypeptides. The information we gain from this permits a number ...

Theme Essay For Dead Poets Society - School/english - Essay

756 words - 4 pages ... Submit research question on due date below 15 points Submit annotated bibliography of sources on due date below 20 points Submit thorough rough draft on due date below 20 points Total 200 points Research question due: Monday, October 24 Annotated bibliography of sources due: Friday, November 4 Rough draft due: Monday, November 14 Final draft due: Wednesday, November 23 Paper length: 5-7 pages Value of assignment: 30% of final grade My paper ...

Biological Molecules And Metabolic Pathways - Robert Clack - Biological Molecules And Metabolic Pathways

1126 words - 5 pages ... made up of polypeptide chains, which are amino acids joined together with peptide bonds the structure that makes up protein or polypeptide is called primary structure. Primary Structure: The unique sequence of amino acids that makes up a protein or polypeptide chain. Peptide bonds are created by enzyme catalysed condensation reactions and broken down by enzyme catalysed hydrolysis reactions. In many part of the body protein is very important ...

Effect Of Antacids On Acidic Substaces - Year 9 - Research Paper

1726 words - 7 pages Free ... acid it neutralises the acid within the stomach. This reaction is called a neutralisation reaction. For example, 2HCI + CaCO^3 = CaCL^2 + H^2O + CO^2. Antacids may work well but this doesn’t mean there isn’t a future for antacids. Scientists have found newer chemicals that are more effective and work faster. Also, a new research paper has found that nanobots can help the body fight indigestion however this technology is far from our reach. The most ...

Pollutants From Buried Army Base In Greenland - Suny Sullivan Composition II - Research Paper

771 words - 4 pages ... 1 Katelin Jester Essay 1 March 8, 2018 Final draft Pollutants from buried army base in Greenland In 1959, the U.S. Army Corps of Engineers built Camp Century, below the ice sheet that covers most of Greenland. This was used as a test site for deploying nuclear missiles at the Soviet Union, however, the public did not know this. It was advertised as a research station, the people in charge of said research were a secret group known as Project ...

Bonus Assignment - Choose A Topic And Write An Essay On It - University Of Waterloo BIOL 439 - Essay

1990 words - 8 pages ... Advances in the Understanding of Egg White Protein Functionality. Trends in Food Science and Technology, 225-232. Nesbet, A. D., Saundry, R. H., Moir, A. J., Fothergill, L. A., & Fothergill, J. E. (1981). The Complete Amino-Acid Sequence of Hen Obalbumin. European Journal of Biochemistry, 335-345. Potter, J. (2016). Cooking for Geeks. Sebastopol: O'Reilly Media Inc. Rhodes, J. (2012, January 20). Meringue Chemistry: The Secrets of Fluff. Retrieved from ...