With sickle cell disease, an inherited group of disorders, red blood cells contort into a sickle shape. The cells die early, leaving a shortage of healthy red blood cells (sickle cell anemia), and can block blood flow causing pain (sickle cell crisis).
Infections, pain, and fatigue are symptoms of sickle cell disease.
Treatments include medications, blood transfusions, and rarely a bone-marrow transplant.
Sickle cell Anemia
What Are the Signs & Symptoms of Sickle Cell Disease?
People with sickle cell disease can have pain crises. In a pain crisis:
· Pain may happen in any part of the body.
· Cold, stress, or dehydration can bring on pain.
· The pain may last a few hours, a few days, or sometimes longer.
· Sometimes pain can be managed at home. But someone with severe pain might need treatment in a hospital.
People with sickle cell disease often have a low number of red blood cells, or anemia. Signs of anemia include:
· paleness, often seen in the skin, lips, or nailbeds
· being short of breath
· feeling lightheaded
· being irritable
· trouble paying attention
· a fast heartbeat
People with sickle cell anemia may have jaundice . This happens because the sickle-shaped red blood cells break down faster than normal cells. Jaundice can make the skin and whites of the eyes look yellow.
What Problems Can Happen?
People with sickle cell disease...